ARHGEF9

Across TCGA patient cohorts, ARHGEF9 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,203 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGEF9-associated proteins across cancer lineages are EIF3K, EIF3M, and RPL5. Each is linked with ARHGEF9 in more than 6 cancer types. Because this analysis shows association rather than direction, both ARHGEF9-to-partner and partner-to-ARHGEF9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF9 versus EIF3K in HNSC, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF9→partner) and Y-score (partner→ARHGEF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EIF3K →	-0.178	-0.469	<.001	.002	3	6
HNSC	EIF3M →	-0.256	-0.639	<.001	<.001	3	6
CCRCC	RPL5 →	-0.212	-0.377	.001	.001	2	7
GBM	RPL7 →	-0.388	-0.526	<.001	<.001	3	6
PDAC	CNN3 →	+0.459	+0.261	<.001	<.001	3	5
HNSC	EIF3H →	-0.174	-0.458	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,203 associations by consensus.

ARHGEF9 vs EIF3K — HNSC

Explore this scatter interactively →