ARHGEF7

Across TCGA cell cohorts, ARHGEF7 RNA expression is significantly associated with the RNA expression of many other genes, with 11,446 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARHGEF7-associated genes across cancer lineages are TUBGCP3, CUL4A, and UPF3A. Each is linked with ARHGEF7 in more than 18 cancer types. Because this analysis shows association rather than direction, both ARHGEF7-to-partner and partner-to-ARHGEF7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF7 versus TUBGCP3 in LUNG_SCLC, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF7→partner) and Y-score (partner→ARHGEF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	TUBGCP3 →	+1.230	+1.746	<.001	<.001	3	19
BLOOD_Myeloma	CUL4A →	+1.109	+0.753	<.001	<.001	3	19
OESOPHAGUS	UPF3A →	+1.235	+1.331	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	ARGLU1 →	+1.467	+0.829	<.001	<.001	3	18
LUNG_SCLC	TPP2 →	+1.155	+1.947	<.001	<.001	3	18
LIVER	ABHD13 →	+0.916	+0.827	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,446 associations by consensus.

ARHGEF7 vs TUBGCP3 — LUNG_SCLC

Explore this scatter interactively →