ARHGEF7

Across TCGA cell cohorts, ARHGEF7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,461 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARHGEF7-associated GO terms across cancer lineages are Ribosomal protein import into nucleus, Positive regulation of lamellipodium morphogenesis, and Regulation of RNA stability. Each is linked with ARHGEF7 in more than 17 cancer types. Because this analysis shows association rather than direction, both ARHGEF7-to-partner and partner-to-ARHGEF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal protein import into nucleus grouped by ARHGEF7-low versus ARHGEF7-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF7→partner) and Y-score (partner→ARHGEF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Ribosomal protein import into nucleus →	+0.112	+1.184	.005	<.001	3	18
STOMACH	Positive regulation of lamellipodium morphogenesis →	+0.220	+1.023	.001	.001	3	16
SOFT_TISSUE	Regulation of RNA stability →	+0.061	+0.705	<.001	.001	3	15
OVARY	Post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.094	+0.700	<.001	<.001	3	14
BLOOD_Leukemia	Copper ion export →	-0.178	-0.977	<.001	<.001	3	13
LARGE_INTESTINE	Phosphatidylinositol biosynthetic process →	+0.050	+0.778	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,461 associations by consensus.

Ribosomal protein import into nucleus by ARHGEF7 expression — STOMACH

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