ARHGEF6

Across TCGA cell cohorts, ARHGEF6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,080 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ARHGEF6-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Regulation of transepithelial transport, and Regulation of focal adhesion assembly. Each is linked with ARHGEF6 in more than 9 cancer types. Because this analysis shows association rather than direction, both ARHGEF6-to-partner and partner-to-ARHGEF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by ARHGEF6-low versus ARHGEF6-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF6→partner) and Y-score (partner→ARHGEF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of focal adhesion assembly →	+0.142	+1.053	<.001	<.001	3	10
CNS	Regulation of transepithelial transport →	+0.071	+1.375	.002	.001	3	9
CNS	Regulation of focal adhesion assembly →	+0.072	+1.360	<.001	<.001	3	9
CNS	Regulation of cell-substrate junction assembly →	+0.072	+1.360	<.001	<.001	3	9
LARGE_INTESTINE	Process utilizing autophagic mechanism →	+0.055	+0.211	<.001	.001	2	10
OVARY	Regulation of angiotensin-activated signaling pathway →	+0.129	+0.905	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,080 associations by consensus.

Positive regulation of focal adhesion assembly by ARHGEF6 expression — OVARY

Explore this box plot interactively →