ARHGEF39

Across TCGA patient cohorts, ARHGEF39 protein abundance is significantly associated with the RNA expression of many other genes, with 6,216 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGEF39-associated genes across cancer lineages are SNORA70F, RPL35AP23, and GABRA4. Each is linked with ARHGEF39 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGEF39-to-partner and partner-to-ARHGEF39 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF39 versus SNORA70F in UCEC, with a Pearson correlation of -0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF39→partner) and Y-score (partner→ARHGEF39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORA70F →	-2.127	-1.432	.002	<.001	3	2
OV	RPL35AP23 →	+0.825	+1.061	<.001	.008	2	2
LSCC	GABRA4 →	+0.005	+0.920	.009	.002	3	1
LSCC	ID4 →	-1.482	-0.293	.001	.006	3	1
LSCC	NPM1P34 →	+0.130	+0.962	<.001	.004	3	1
LSCC	RN7SL26P →	+0.254	+0.848	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,216 associations by consensus.

ARHGEF39 vs SNORA70F — UCEC

Explore this scatter interactively →