ARHGEF39

Across TCGA cell cohorts, ARHGEF39 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARHGEF39-associated genes across cancer lineages are FAM187B, UTF1, and ENTHD1. Each is linked with ARHGEF39 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGEF39-to-partner and partner-to-ARHGEF39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM187B grouped by ARHGEF39-low versus ARHGEF39-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF39→partner) and Y-score (partner→ARHGEF39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	FAM187B →	+0.052	+5.643	<.001	.002	3	1
LARGE_INTESTINE	UTF1 →	+0.018	+3.632	<.001	.003	3	1
LARGE_INTESTINE	ENTHD1 →	+0.030	+3.554	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

FAM187B by ARHGEF39 expression — BLOOD_Lymphoma

Explore this box plot interactively →