ARHGEF38

Across TCGA patient cohorts, ARHGEF38 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,113 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ARHGEF38-associated proteins across cancer lineages are ARHGEF38_S55, DDAH1, and LRBA. Each is linked with ARHGEF38 in more than 6 cancer types. Because this analysis shows association rather than direction, both ARHGEF38-to-partner and partner-to-ARHGEF38 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF38 versus ARHGEF38_S55 in HNSC, with a Pearson correlation of 0.82.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF38→partner) and Y-score (partner→ARHGEF38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ARHGEF38_S55 →	+1.759	+1.047	<.001	<.001	3	7
LUAD	DDAH1 →	+0.590	+0.979	<.001	<.001	3	6
BRCA	LRBA →	+0.409	+1.319	<.001	<.001	3	6
HNSC	MISP3_S91 →	+0.948	+1.213	<.001	<.001	3	6
LSCC	TJP3 →	+0.564	+1.082	<.001	<.001	3	6
UCEC	CHDH →	+0.431	+0.726	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,113 associations by consensus.

ARHGEF38 vs ARHGEF38_S55 — HNSC

Explore this scatter interactively →