ARHGEF38

Across TCGA cell cohorts, ARHGEF38 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,431 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ARHGEF38-associated GO terms across cancer lineages are Collagen fibril organization, tRNA wobble uridine modification, and Establishment of epithelial cell apical/basal polarity. Each is linked with ARHGEF38 in more than 9 cancer types. Because this analysis shows association rather than direction, both ARHGEF38-to-partner and partner-to-ARHGEF38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Collagen fibril organization grouped by ARHGEF38-low versus ARHGEF38-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF38→partner) and Y-score (partner→ARHGEF38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Collagen fibril organization →	-0.197	-1.453	<.001	<.001	3	10
STOMACH	tRNA wobble uridine modification →	-0.059	-1.483	.004	<.001	3	8
STOMACH	Establishment of epithelial cell apical/basal polarity →	-0.204	-1.300	<.001	.005	3	8
PANCREAS	Lateral line system development →	+1.556	+0.641	<.001	.009	3	8
LUNG_NSCLC_LUSC	Regulation of atrial cardiac muscle cell membrane depolarization →	-1.607	-1.018	<.001	<.001	3	8
LARGE_INTESTINE	Positive regulation of sodium ion transport →	+0.182	+0.973	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,431 associations by consensus.

Collagen fibril organization by ARHGEF38 expression — BREAST

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