Across TCGA patient cohorts, ARHGEF37 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,057 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGEF37-associated proteins across cancer lineages are BIN3, ARHGEF37_S251, and HSPA13. Each is linked with ARHGEF37 in more than 8 cancer types. Because this analysis shows association rather than direction, both ARHGEF37-to-partner and partner-to-ARHGEF37 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF37→partner) and Y-score (partner→ARHGEF37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BIN3 →	+0.448	+1.158	<.001	<.001	3	9
PDAC	ARHGEF37_S251 →	+0.986	+0.837	<.001	<.001	3	7
LSCC	HSPA13 →	-0.441	-0.846	<.001	<.001	3	6
HNSC	TACC2 →	+0.371	+0.750	<.001	.003	2	6
HNSC	ARHGAP32 →	+0.328	+0.707	<.001	<.001	3	5
HNSC	MAST4 →	+0.330	+0.809	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,057 associations by consensus.

Exploration

ARHGEF37 survival (RNA) · tumor vs normal (RNA) · all ARHGEF37 data types