Across TCGA patient cohorts, ARHGEF37 protein abundance is significantly associated with the RNA expression of many other genes, with 15,098 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ARHGEF37-associated genes across cancer lineages are NCAPH, CENPO, and HJURP. Each is linked with ARHGEF37 in more than 8 cancer types. Because this analysis shows association rather than direction, both ARHGEF37-to-partner and partner-to-ARHGEF37 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF37→partner) and Y-score (partner→ARHGEF37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NCAPH →	-0.790	-0.413	<.001	<.001	3	9
UCEC	CENPO →	-0.640	-0.395	<.001	<.001	3	9
GBM	HJURP →	-0.967	-0.415	<.001	<.001	3	8
GBM	AURKB →	-0.935	-0.401	<.001	<.001	3	8
LUAD	POLQ →	-0.904	-0.363	<.001	<.001	3	8
GBM	GTSE1 →	-0.860	-0.378	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,098 associations by consensus.

Exploration

ARHGEF37 survival (RNA) · tumor vs normal (RNA) · all ARHGEF37 data types