Across TCGA patient cohorts, ARHGEF37 mutation is significantly associated with the RNA expression of many other genes, with 1,066 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGEF37-associated genes across cancer lineages are DHX37, NUDC, and SNF8. Each is linked with ARHGEF37 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARHGEF37-to-partner and partner-to-ARHGEF37 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF37→partner) and Y-score (partner→ARHGEF37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DHX37 →	+0.406	+2.329	.003	.003	3	3
SKCM	NUDC →	+0.506	+2.604	<.001	.005	3	3
UCEC	SNF8 →	+0.352	+2.617	.004	<.001	3	2
UCEC	TKT →	+0.630	+2.584	.001	.001	3	2
UCEC	CDC25A →	+0.602	+3.931	.004	<.001	3	2
UCEC	NDUFAF2 →	+0.519	+2.595	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,066 associations by consensus.

Exploration

ARHGEF37 survival (RNA) · tumor vs normal (RNA) · all ARHGEF37 data types