Across TCGA patient cohorts, ARHGEF35 protein abundance is significantly associated with the RNA expression of many other genes, with 3,844 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGEF35-associated genes across cancer lineages are CTAGE4, ARHGEF35-AS1, and ARHGEF34P. Each is linked with ARHGEF35 in more than 4 cancer types. Because this analysis shows association rather than direction, both ARHGEF35-to-partner and partner-to-ARHGEF35 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF35→partner) and Y-score (partner→ARHGEF35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CTAGE4 →	+0.601	+0.545	<.001	<.001	3	5
CCRCC	ARHGEF35-AS1 →	+0.664	+0.453	.001	<.001	3	4
LSCC	ARHGEF34P →	+0.766	+0.434	<.001	<.001	3	4
UCEC	OR2A7 →	+0.791	+0.581	.004	.004	3	4
LSCC	ARHGEF5 →	+0.771	+0.302	<.001	<.001	3	4
COAD	PRRG4 →	+1.314	+0.939	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,844 associations by consensus.

Exploration

ARHGEF35 survival (RNA) · tumor vs normal (RNA) · all ARHGEF35 data types