Across TCGA cell cohorts, ARHGEF33 mutation is significantly associated with the RNA expression of many other genes, with 169 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARHGEF33-associated genes across cancer lineages are ACSM2A, OR13C9, and RSPH6A. Each is linked with ARHGEF33 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGEF33-to-partner and partner-to-ARHGEF33 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF33→partner) and Y-score (partner→ARHGEF33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ACSM2A →	+0.047	+4.029	.003	.009	3	2
OVARY	OR13C9 →	+0.041	+4.228	<.001	.006	3	1
CNS	RSPH6A →	+0.033	+3.874	<.001	.006	3	1
CNS	ZNF831 →	+0.070	+3.832	<.001	.005	3	1
CNS	IL22RA2 →	+0.425	+4.584	<.001	.001	3	1
CNS	OR6C2 →	+0.095	+4.044	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 169 associations by consensus.

Exploration

ARHGEF33 survival (RNA) · tumor vs normal (RNA) · all ARHGEF33 data types