ARHGEF26

Across TCGA patient cohorts, ARHGEF26 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,594 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGEF26-associated proteins across cancer lineages are ARHGEF26_S392, ARHGEF26_S222, and ARHGEF26_S422. Each is linked with ARHGEF26 in more than 8 cancer types. Because this analysis shows association rather than direction, both ARHGEF26-to-partner and partner-to-ARHGEF26 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF26 versus ARHGEF26_S392 in LSCC, with a Pearson correlation of 0.91.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF26→partner) and Y-score (partner→ARHGEF26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGEF26_S392 →	+1.419	+1.776	<.001	<.001	3	9
HNSC	ARHGEF26_S222 →	+1.074	+1.431	<.001	<.001	3	8
LSCC	ARHGEF26_S422 →	+1.224	+1.670	<.001	<.001	3	8
LSCC	ARHGEF26_S80 →	+1.108	+1.445	<.001	<.001	3	7
UCEC	KYNU →	-0.777	-0.464	<.001	.002	3	6
BRCA	TCEAL1 →	+0.666	+0.842	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,594 associations by consensus.

ARHGEF26 vs ARHGEF26_S392 — LSCC

Explore this scatter interactively →