ARHGEF26

Across TCGA patient cohorts, ARHGEF26 protein abundance is significantly associated with the RNA expression of many other genes, with 10,655 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGEF26-associated genes across cancer lineages are DIPK2A, AIF1L, and PTP4A2. Each is linked with ARHGEF26 in more than 3 cancer types. Because this analysis shows association rather than direction, both ARHGEF26-to-partner and partner-to-ARHGEF26 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF26 versus DIPK2A in HNSC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF26→partner) and Y-score (partner→ARHGEF26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DIPK2A →	+1.748	+1.116	.001	<.001	3	4
COAD	AIF1L →	+1.863	+2.193	.004	.008	3	3
PDAC	PTP4A2 →	-0.463	-0.827	.004	.007	3	3
LSCC	C6orf15 →	+2.248	+0.483	<.001	<.001	3	3
GBM	HRH2 →	-0.684	-0.364	.001	.006	3	3
BRCA	KCNH1 →	+0.507	+0.473	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,655 associations by consensus.

ARHGEF26 vs DIPK2A — HNSC

Explore this scatter interactively →