ARHGEF26-AS1

Across TCGA pan-cancer cohorts, ARHGEF26-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ARHGEF26-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher ARHGEF26-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ARHGEF26-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and LUAD show a favorable association.

MESO, OV, and LUAD are the cancer types where ARHGEF26-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	II,III,IV	0.236	0.738	<.001	119	view →
OV	DFS	Tertile	III,IV	0.607	0.459	<.001	82	view →
LUAD	OS	Tertile	All	0.852	0.731	<.001	56	view →
KIRP	DFS	Tertile	All	0.766	0.953	<.001	55	view →
COAD	DFS	Tertile	IV	0.294	0.621	<.001	43	view →
LGG	DFS	Median	All	0.507	0.329	.001	36	view →
KICH	OS	Quartile	III,IV	0.159	0.876	.001	32	view →
PAAD	DFS	Tertile	All	0.442	0.185	.001	26	view →
STAD	OS	Quartile	IV	0.585	0.154	.015	18	view →
SARC	OS	Quartile	All	0.957	0.782	.003	11	view →
ACC	OS	Median	II,III,IV	0.765	0.921	.009	11	view →
THCA	DFS	Quartile	III,IV	1.000	0.685	.017	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ARHGEF26-AS1–MESO (OS)

Open the MESO breakdown →