ARHGEF19

Across TCGA patient cohorts, ARHGEF19 protein abundance is significantly associated with the RNA expression of many other genes, with 2,742 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGEF19-associated genes across cancer lineages are IDH2, SLC8A1-AS1, and RNA5SP82. Each is linked with ARHGEF19 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGEF19-to-partner and partner-to-ARHGEF19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF19 versus IDH2 in BRCA, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF19→partner) and Y-score (partner→ARHGEF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IDH2 →	+0.752	+0.557	.003	.002	3	2
LSCC	SLC8A1-AS1 →	-0.459	-0.660	<.001	<.001	3	2
UCEC	RNA5SP82 →	-1.833	-0.286	.002	.005	3	2
HNSC	LILRB5 →	-0.810	-0.443	<.001	.009	3	2
HNSC	C2 →	-0.715	-0.593	.002	.006	3	2
HNSC	PCED1B →	-0.859	-0.851	.005	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,742 associations by consensus.

ARHGEF19 vs IDH2 — BRCA

Explore this scatter interactively →