ARHGEF18

Across TCGA patient cohorts, ARHGEF18 protein abundance is significantly associated with the RNA expression of many other genes, with 9,597 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGEF18-associated genes across cancer lineages are MEFV, PCGF1, and CLEC4D. Each is linked with ARHGEF18 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARHGEF18-to-partner and partner-to-ARHGEF18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF18 versus MEFV in LSCC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF18→partner) and Y-score (partner→ARHGEF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MEFV →	+0.599	+0.301	<.001	<.001	3	3
LSCC	PCGF1 →	-0.324	-0.275	<.001	<.001	3	3
LSCC	CLEC4D →	+0.681	+0.322	<.001	<.001	3	3
LSCC	FPR2 →	+1.123	+0.432	<.001	<.001	3	3
BRCA	SELL →	+1.136	+0.338	.001	.001	3	3
LSCC	BRWD1-IT1 →	-0.474	-0.236	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,597 associations by consensus.

ARHGEF18 vs MEFV — LSCC

Explore this scatter interactively →