ARHGEF17

Across TCGA patient cohorts, ARHGEF17 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,007 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ARHGEF17-associated proteins across cancer lineages are ARHGEF17_S507, ARHGEF17_T1991, and PRKG1. Each is linked with ARHGEF17 in more than 8 cancer types. Because this analysis shows association rather than direction, both ARHGEF17-to-partner and partner-to-ARHGEF17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF17 versus ARHGEF17_S507 in CCRCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF17→partner) and Y-score (partner→ARHGEF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ARHGEF17_S507 →	+0.773	+0.906	<.001	<.001	3	8
LSCC	ARHGEF17_T1991 →	+0.844	+0.727	<.001	<.001	3	8
OV	PRKG1 →	+0.622	+0.855	.002	.008	2	9
BRCA	PCOLCE →	+0.766	+0.770	<.001	<.001	3	8
LSCC	ILK →	+0.432	+0.669	<.001	<.001	3	8
CCRCC	KANK2 →	+0.494	+0.666	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,007 associations by consensus.

ARHGEF17 vs ARHGEF17_S507 — CCRCC

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