Across TCGA cell cohorts, ARHGEF15 RNA expression is significantly associated with the go_rna of many other GO terms, with 165 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARHGEF15-associated GO terms across cancer lineages are COPII-coated vesicle budding, Maintenance of protein localization in organelle, and Nitric oxide metabolic process. Each is linked with ARHGEF15 in more than 3 cancer types. Because this analysis shows association rather than direction, both ARHGEF15-to-partner and partner-to-ARHGEF15 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF15→partner) and Y-score (partner→ARHGEF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	COPII-coated vesicle budding →	+0.069	+0.028	<.001	.005	3	4
BLOOD_Leukemia	Maintenance of protein localization in organelle →	+0.072	+0.082	<.001	.005	3	3
SKIN	Nitric oxide metabolic process →	-0.112	-0.022	<.001	.007	3	2
LUNG_NSCLC_LUAD	Positive regulation of viral genome replication →	+0.070	+0.017	<.001	.006	3	2
LUNG_NSCLC_LUAD	Negative regulation of JNK cascade →	+0.048	+0.014	.002	.008	3	2
BLOOD_Leukemia	Promoter clearance during DNA-templated transcription →	+0.053	+0.038	.003	.008	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 165 associations by consensus.

Exploration

ARHGEF15 survival (RNA) · tumor vs normal (RNA) · all ARHGEF15 data types