Across TCGA cell cohorts, ARHGEF15 mutation is significantly associated with the mutation status of many other genes, with 3,906 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARHGEF15-associated genes across cancer lineages are COL5A1, URB2, and XYLT2. Each is linked with ARHGEF15 in more than 3 cancer types. Because this analysis shows association rather than direction, both ARHGEF15-to-partner and partner-to-ARHGEF15 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF15→partner) and Y-score (partner→ARHGEF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	COL5A1 →	+3.087	+4.000	.008	.008	1	4
BREAST	URB2 →	+3.121	+4.339	.005	.005	1	4
BREAST	XYLT2 →	+4.857	+4.297	.009	.009	1	4
OVARY	ZNFX1 →	+4.977	+4.415	.007	.007	1	4
OVARY	CEP250 →	+4.977	+4.415	.007	.007	1	4
LUNG_NSCLC_LUAD	ABCC5 →	+3.584	+4.063	.003	.003	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,906 associations by consensus.

Exploration

ARHGEF15 survival (RNA) · tumor vs normal (RNA) · all ARHGEF15 data types