Across TCGA cell cohorts, ARHGEF12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,564 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARHGEF12-associated GO terms across cancer lineages are Cytosolic transport, Post-Golgi vesicle-mediated transport, and Rho-activating G protein-coupled receptor signaling pathway. Each is linked with ARHGEF12 in more than 14 cancer types. Because this analysis shows association rather than direction, both ARHGEF12-to-partner and partner-to-ARHGEF12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF12→partner) and Y-score (partner→ARHGEF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.077	+1.328	<.001	<.001	3	15
OESOPHAGUS	Post-Golgi vesicle-mediated transport →	+0.086	+1.079	<.001	.004	3	15
KIDNEY	Rho-activating G protein-coupled receptor signaling pathway →	+0.189	+1.184	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.058	+0.826	<.001	<.001	3	13
SOFT_TISSUE	Peptidyl-serine phosphorylation →	+0.068	+1.144	<.001	<.001	3	13
LIVER	Ether catabolic process →	+0.215	+1.037	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,564 associations by consensus.

Exploration

ARHGEF12 survival (RNA) · tumor vs normal (RNA) · all ARHGEF12 data types