ARHGEF11

Across TCGA cell cohorts, ARHGEF11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,805 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARHGEF11-associated GO terms across cancer lineages are Cytosolic transport, Post-Golgi vesicle-mediated transport, and Vacuole organization. Each is linked with ARHGEF11 in more than 15 cancer types. Because this analysis shows association rather than direction, both ARHGEF11-to-partner and partner-to-ARHGEF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by ARHGEF11-low versus ARHGEF11-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF11→partner) and Y-score (partner→ARHGEF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Cytosolic transport →	+0.062	+0.817	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Post-Golgi vesicle-mediated transport →	+0.070	+1.139	.004	.001	3	16
OESOPHAGUS	Vacuole organization →	+0.052	+0.720	.005	.005	3	16
OESOPHAGUS	Endosomal transport →	+0.054	+0.792	<.001	<.001	3	15
OESOPHAGUS	Golgi vesicle transport →	+0.084	+0.889	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Mitotic cytokinesis →	+0.089	+1.572	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,805 associations by consensus.

Cytosolic transport by ARHGEF11 expression — CNS

Explore this box plot interactively →