ARHGEF10

Across TCGA patient cohorts, ARHGEF10 protein abundance is significantly associated with the RNA expression of many other genes, with 11,937 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGEF10-associated genes across cancer lineages are PMP22, SYDE1, and CAV1. Each is linked with ARHGEF10 in more than 7 cancer types. Because this analysis shows association rather than direction, both ARHGEF10-to-partner and partner-to-ARHGEF10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF10 versus PMP22 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF10→partner) and Y-score (partner→ARHGEF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PMP22 →	+1.180	+0.558	<.001	<.001	3	8
OV	SYDE1 →	+0.960	+0.414	<.001	.003	3	7
GBM	CAV1 →	+1.308	+0.316	<.001	<.001	3	7
OV	SPARC →	+2.018	+0.555	<.001	<.001	3	7
OV	CALD1 →	+0.948	+0.359	<.001	<.001	3	7
OV	GFPT2 →	+1.570	+0.480	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,937 associations by consensus.

ARHGEF10 vs PMP22 — OV

Explore this scatter interactively →