ARHGDIB

Across TCGA cell cohorts, ARHGDIB RNA expression is significantly associated with the go_rna of many other GO terms, with 5,008 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ARHGDIB-associated GO terms across cancer lineages are Small GTPase-mediated signal transduction, Rho protein signal transduction, and Regulation of proteolysis. Each is linked with ARHGDIB in more than 12 cancer types. Because this analysis shows association rather than direction, both ARHGDIB-to-partner and partner-to-ARHGDIB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Small GTPase-mediated signal transduction grouped by ARHGDIB-low versus ARHGDIB-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGDIB→partner) and Y-score (partner→ARHGDIB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Small GTPase-mediated signal transduction →	+0.076	+5.175	<.001	<.001	3	13
OESOPHAGUS	Rho protein signal transduction →	+0.113	+3.100	<.001	<.001	3	12
LIVER	Regulation of proteolysis →	+0.099	+3.474	<.001	<.001	2	12
LUNG_NSCLC_LUAD	Cellular response to environmental stimulus →	+0.030	+2.270	.005	.006	2	12
LUNG_NSCLC_LUAD	Cellular response to abiotic stimulus →	+0.030	+2.270	.005	.006	2	12
LUNG_NSCLC_LUSC	Epinephrine transport →	-1.288	-3.767	.003	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,008 associations by consensus.

Small GTPase-mediated signal transduction by ARHGDIB expression — URINARY_TRACT

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