ARHGDIB

Across TCGA cell cohorts, ARHGDIB protein abundance is significantly associated with the go_rna of many other GO terms, with 1,332 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARHGDIB-associated GO terms across cancer lineages are Negative regulation of hydrogen peroxide biosynthetic process, Cadmium ion transmembrane transport, and Succinate transmembrane transport. Each is linked with ARHGDIB in more than 2 cancer types. Because this analysis shows association rather than direction, both ARHGDIB-to-partner and partner-to-ARHGDIB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of hydrogen peroxide biosynthetic process grouped by ARHGDIB-low versus ARHGDIB-high in LARGE_INTESTINE.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGDIB→partner) and Y-score (partner→ARHGDIB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of hydrogen peroxide biosynthetic process →	+0.242	+1.551	<.001	.007	3	3
LUNG_NSCLC_LUAD	Cadmium ion transmembrane transport →	-0.269	-0.774	.001	<.001	3	3
LUNG_NSCLC_LUAD	Succinate transmembrane transport →	-0.335	-0.721	<.001	.001	3	3
LUNG_SCLC	Regulation of receptor localization to synapse →	-0.078	-1.056	.005	<.001	3	3
LUNG_NSCLC_LUAD	Cadmium ion transport →	-0.269	-0.774	.001	<.001	3	3
LUNG_NSCLC_LUAD	Succinate transport →	-0.335	-0.721	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,332 associations by consensus.

Negative regulation of hydrogen peroxide biosynthetic process by ARHGDIB expression — LARGE_INTESTINE

Explore this box plot interactively →