ARHGAP9

Across TCGA patient cohorts, ARHGAP9 mutation is significantly associated with the RNA expression of many other genes, with 4,938 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP9-associated genes across cancer lineages are CDCA2, USP15, and C18orf54. Each is linked with ARHGAP9 in more than 3 cancer types. Because this analysis shows association rather than direction, both ARHGAP9-to-partner and partner-to-ARHGAP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDCA2 grouped by ARHGAP9-low versus ARHGAP9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP9→partner) and Y-score (partner→ARHGAP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDCA2 →	+0.899	+2.632	<.001	<.001	3	4
UCEC	USP15 →	+0.425	+2.632	<.001	<.001	3	4
UCEC	C18orf54 →	+0.535	+1.807	<.001	<.001	3	4
SKCM	CD274 →	+1.008	+2.366	.001	.003	3	3
UCEC	CEP55 →	+0.752	+2.050	<.001	<.001	3	3
SKCM	RMND1 →	+0.522	+3.360	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,938 associations by consensus.

CDCA2 by ARHGAP9 expression — UCEC

Explore this box plot interactively →