ARHGAP9

Across TCGA cell cohorts, ARHGAP9 mutation is significantly associated with the RNA expression of many other genes, with 177 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible ARHGAP9-associated genes across cancer lineages are EMC6, DBX2, and HM13. Each is linked with ARHGAP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP9-to-partner and partner-to-ARHGAP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EMC6 grouped by ARHGAP9-low versus ARHGAP9-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP9→partner) and Y-score (partner→ARHGAP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	EMC6 →	+0.681	+1.378	.005	.007	3	2
BLOOD_Lymphoma	DBX2 →	+0.007	+5.169	<.001	.001	3	2
BLOOD_Myeloma	HM13 →	+0.823	+1.736	.001	.003	3	1
BLOOD_Myeloma	LFNG →	-0.529	-2.906	.005	.001	3	1
BLOOD_Myeloma	SEC61B →	+0.681	+1.807	<.001	<.001	3	1
BLOOD_Myeloma	B9D1 →	+1.187	+2.169	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 177 associations by consensus.

EMC6 by ARHGAP9 expression — BLOOD_Myeloma

Explore this box plot interactively →