ARHGAP6

Across TCGA cell cohorts, ARHGAP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,537 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ARHGAP6-associated GO terms across cancer lineages are Positive regulation of phospholipase C/protein kinase C signal transduction, Positive regulation of stress fiber assembly, and Regulation of myoblast fusion. Each is linked with ARHGAP6 in more than 9 cancer types. Because this analysis shows association rather than direction, both ARHGAP6-to-partner and partner-to-ARHGAP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of phospholipase C/protein kinase C signal transduction grouped by ARHGAP6-low versus ARHGAP6-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP6→partner) and Y-score (partner→ARHGAP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of phospholipase C/protein kinase C signal transduction →	-0.502	-0.856	<.001	<.001	3	10
BONE	Positive regulation of stress fiber assembly →	+0.122	+0.554	.002	<.001	3	6
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.075	+0.381	<.001	.003	3	6
BLOOD_Lymphoma	ATP synthesis coupled electron transport →	+0.063	+0.403	<.001	.002	3	6
BLOOD_Lymphoma	Mitochondrial ATP synthesis coupled electron transport →	+0.063	+0.403	<.001	.002	3	6
SKIN	Amyloid-beta clearance by transcytosis →	+0.094	+1.113	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,537 associations by consensus.

Positive regulation of phospholipase C/protein kinase C signal transduction by ARHGAP6 expression — OVARY

Explore this box plot interactively →