ARHGAP5

Across TCGA patient cohorts, ARHGAP5 protein abundance is significantly associated with the RNA expression of many other genes, with 12,090 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ARHGAP5-associated genes across cancer lineages are ARHGAP5-AS1, STRN3, and SRP54. Each is linked with ARHGAP5 in more than 7 cancer types. Because this analysis shows association rather than direction, both ARHGAP5-to-partner and partner-to-ARHGAP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP5 versus ARHGAP5-AS1 in GBM, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP5→partner) and Y-score (partner→ARHGAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARHGAP5-AS1 →	+0.823	+0.301	<.001	<.001	3	8
BRCA	STRN3 →	+0.669	+0.292	<.001	<.001	3	8
OV	SRP54 →	+0.556	+0.204	<.001	<.001	3	7
LSCC	BCL2L2 →	+0.567	+0.232	<.001	<.001	3	7
HNSC	EAPP →	+0.821	+0.326	.001	<.001	3	7
BRCA	FAM177A1 →	+0.487	+0.186	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,090 associations by consensus.

ARHGAP5 vs ARHGAP5-AS1 — GBM

Explore this scatter interactively →