ARHGAP5

Across TCGA cell cohorts, ARHGAP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,459 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARHGAP5-associated GO terms across cancer lineages are Endosome to lysosome transport, Vesicle tethering to Golgi, and Positive regulation of mRNA catabolic process. Each is linked with ARHGAP5 in more than 13 cancer types. Because this analysis shows association rather than direction, both ARHGAP5-to-partner and partner-to-ARHGAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosome to lysosome transport grouped by ARHGAP5-low versus ARHGAP5-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP5→partner) and Y-score (partner→ARHGAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Endosome to lysosome transport →	+0.053	+0.706	<.001	<.001	3	13
BONE	Vesicle tethering to Golgi →	+0.103	+1.230	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mRNA catabolic process →	+0.066	+0.965	.008	.005	2	14
PANCREAS	Regulation of canonical Wnt signaling pathway →	+0.046	+1.062	<.001	<.001	3	13
OVARY	Host-mediated perturbation of viral process →	+0.076	+0.858	<.001	.001	3	13
OVARY	Post-transcriptional gene silencing →	+0.086	+0.940	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,459 associations by consensus.

Endosome to lysosome transport by ARHGAP5 expression — CNS

Explore this box plot interactively →