ARHGAP44

Across TCGA patient cohorts, ARHGAP44 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,259 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGAP44-associated proteins across cancer lineages are ARHGAP44_S596, NAA50, and RPS2. Each is linked with ARHGAP44 in more than 5 cancer types. Because this analysis shows association rather than direction, both ARHGAP44-to-partner and partner-to-ARHGAP44 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP44 versus ARHGAP44_S596 in GBM, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP44→partner) and Y-score (partner→ARHGAP44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARHGAP44_S596 →	+1.273	+0.705	<.001	<.001	3	6
GBM	NAA50 →	-0.209	-0.768	<.001	<.001	3	5
HNSC	RPS2 →	-0.179	-0.460	<.001	<.001	3	5
GBM	RPS3A →	-0.201	-0.581	<.001	<.001	3	5
GBM	SEPTIN4 →	+0.671	+0.616	<.001	<.001	3	5
HNSC	DCLK1 →	+0.657	+0.617	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,259 associations by consensus.

ARHGAP44 vs ARHGAP44_S596 — GBM

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