ARHGAP44

Across TCGA cell cohorts, ARHGAP44 mutation is significantly associated with the RNA expression of many other genes, with 1,181 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARHGAP44-associated genes across cancer lineages are C1QTNF7, ARGFX, and OR2W1. Each is linked with ARHGAP44 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP44-to-partner and partner-to-ARHGAP44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1QTNF7 grouped by ARHGAP44-low versus ARHGAP44-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP44→partner) and Y-score (partner→ARHGAP44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C1QTNF7 →	+0.057	+2.301	<.001	.001	3	2
LUNG_NSCLC_LUAD	ARGFX →	+0.014	+4.662	.002	.005	3	1
LUNG_NSCLC_LUAD	OR2W1 →	+0.021	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	PLSCR5 →	+0.614	+4.212	<.001	.007	3	1
LUNG_NSCLC_LUAD	PRAMEF11 →	+0.004	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR5V1 →	+0.023	+4.947	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,181 associations by consensus.

C1QTNF7 by ARHGAP44 expression — LARGE_INTESTINE

Explore this box plot interactively →