ARHGAP42P4

Across TCGA pan-cancer cohorts, ARHGAP42P4 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated ARHGAP42P4 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher ARHGAP42P4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ARHGAP42P4 expression acts as an unfavorable survival marker.

THCA, LUSC, and KIRP are the cancer types where ARHGAP42P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	II,III,IV	0.116	0.705	<.001	54	view →
LUSC	OS	Tertile	III,IV	0.130	0.750	<.001	54	view →
KIRP	OS	Tertile	III,IV	0.097	0.518	.008	45	view →
HNSC	DFS	Tertile	IV	0.416	0.657	.004	36	view →
LGG	DFS	Tertile	All	0.493	0.752	<.001	36	view →
READ	OS	Tertile	All	0.281	0.736	.009	33	view →
LUAD	OS	Tertile	II,III,IV	0.333	0.690	.006	30	view →
SARC	OS	Tertile	All	0.584	0.841	.009	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

ARHGAP42P4–THCA (DFS)

Open the THCA breakdown →