ARHGAP42

Across TCGA pan-cancer cohorts, ARHGAP42 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ARHGAP42 data layer compared with 22 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher ARHGAP42 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ARHGAP42 expression acts as an unfavorable survival marker.

READ, UCEC, and LIHC are the cancer types where ARHGAP42 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Median	II,III,IV	0.111	0.919	<.001	36	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LIHC	OS	Median	All	0.488	0.779	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ARHGAP42–READ (OS)

Open the READ breakdown →