ARHGAP42

Across TCGA patient cohorts, ARHGAP42 protein abundance is significantly associated with the RNA expression of many other genes, with 12,409 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGAP42-associated genes across cancer lineages are RN7SKP115, SRPX2, and ANTXR2. Each is linked with ARHGAP42 in more than 5 cancer types. Because this analysis shows association rather than direction, both ARHGAP42-to-partner and partner-to-ARHGAP42 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP42 versus RN7SKP115 in CCRCC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP42→partner) and Y-score (partner→ARHGAP42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RN7SKP115 →	+0.736	+0.230	<.001	<.001	3	6
BRCA	SRPX2 →	+0.916	+0.406	.004	.003	3	5
UCEC	ANTXR2 →	+0.966	+0.383	<.001	<.001	3	5
OV	PODN →	+1.620	+0.561	<.001	<.001	3	5
BRCA	MAML2 →	+1.071	+0.431	<.001	<.001	3	5
LSCC	FAT4 →	+0.737	+0.279	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,409 associations by consensus.

ARHGAP42 vs RN7SKP115 — CCRCC

Explore this scatter interactively →