ARHGAP42

Across TCGA cell cohorts, ARHGAP42 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,373 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ARHGAP42-associated GO terms across cancer lineages are Peptidyl-tyrosine modification, Regulation of canonical Wnt signaling pathway, and Response to insulin. Each is linked with ARHGAP42 in more than 7 cancer types. Because this analysis shows association rather than direction, both ARHGAP42-to-partner and partner-to-ARHGAP42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-tyrosine modification grouped by ARHGAP42-low versus ARHGAP42-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP42→partner) and Y-score (partner→ARHGAP42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Peptidyl-tyrosine modification →	+0.037	+0.778	.009	.007	3	8
PANCREAS	Regulation of canonical Wnt signaling pathway →	+0.037	+1.020	.003	.006	3	8
BONE	Response to insulin →	+0.037	+1.286	.004	.002	3	8
BLOOD_Myeloma	Regulation of L-glutamate import across plasma membrane →	+0.166	+1.109	.005	.005	3	7
PANCREAS	Regulation of actin filament length →	+0.081	+1.223	.002	<.001	3	7
BONE	Regulation of intracellular transport →	+0.056	+1.536	.002	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,373 associations by consensus.

Peptidyl-tyrosine modification by ARHGAP42 expression — PANCREAS

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