ARHGAP40

Across TCGA patient cohorts, ARHGAP40 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible ARHGAP40-associated genes across cancer lineages are CD300LD and LINC01708. Each is linked with ARHGAP40 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP40-to-partner and partner-to-ARHGAP40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300LD grouped by ARHGAP40-low versus ARHGAP40-high in SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP40→partner) and Y-score (partner→ARHGAP40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	CD300LD →	+0.131	+4.847	<.001	.009	3	1
COAD	LINC01708 →	+0.148	+6.003	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD300LD by ARHGAP40 expression — SCLC

Explore this box plot interactively →