ARHGAP4

Across TCGA patient cohorts, ARHGAP4 protein abundance is significantly associated with the RNA expression of many other genes, with 21,772 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGAP4-associated genes across cancer lineages are NKG7, IL10RA, and CD86. Each is linked with ARHGAP4 in more than 9 cancer types. Because this analysis shows association rather than direction, both ARHGAP4-to-partner and partner-to-ARHGAP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP4 versus NKG7 in UCEC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP4→partner) and Y-score (partner→ARHGAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NKG7 →	+1.964	+0.471	<.001	<.001	3	10
GBM	IL10RA →	+1.410	+0.725	<.001	<.001	3	10
GBM	CD86 →	+1.230	+0.692	<.001	<.001	3	10
GBM	PLEK →	+1.358	+0.713	<.001	<.001	3	10
HNSC	SASH3 →	+1.323	+0.557	<.001	<.001	3	10
HNSC	FAM78A →	+0.864	+0.482	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,772 associations by consensus.

ARHGAP4 vs NKG7 — UCEC

Explore this scatter interactively →