ARHGAP4

Across TCGA patient cohorts, ARHGAP4 protein abundance is significantly associated with the protein abundance of many other proteins, with 35,028 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGAP4-associated proteins across cancer lineages are APBB1IP, ARHGAP15, and SAMSN1_S23. Each is linked with ARHGAP4 in more than 9 cancer types. Because this analysis shows association rather than direction, both ARHGAP4-to-partner and partner-to-ARHGAP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP4 versus APBB1IP in GBM, with a Pearson correlation of 0.84.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP4→partner) and Y-score (partner→ARHGAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	APBB1IP →	+0.723	+0.676	<.001	<.001	3	10
GBM	ARHGAP15 →	+0.769	+0.684	<.001	<.001	3	10
LSCC	SAMSN1_S23 →	+0.759	+0.470	<.001	<.001	3	10
GBM	WAS →	+0.884	+0.790	<.001	<.001	3	10
BRCA	CYBB →	+1.037	+0.490	<.001	<.001	3	10
GBM	DOCK2 →	+0.863	+0.766	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 35,028 associations by consensus.

ARHGAP4 vs APBB1IP — GBM

Explore this scatter interactively →