ARHGAP4

Across TCGA cell cohorts, ARHGAP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,501 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ARHGAP4-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Positive regulation of DNA recombination, and Regulation of DNA recombination. Each is linked with ARHGAP4 in more than 10 cancer types. Because this analysis shows association rather than direction, both ARHGAP4-to-partner and partner-to-ARHGAP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by ARHGAP4-low versus ARHGAP4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP4→partner) and Y-score (partner→ARHGAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of DNA metabolic process →	+0.066	+2.690	<.001	<.001	3	11
BONE	Positive regulation of DNA recombination →	+0.098	+3.084	<.001	<.001	3	9
BONE	Regulation of DNA recombination →	+0.111	+3.870	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.104	-1.104	.001	.008	3	8
OESOPHAGUS	mRNA splice site recognition →	+0.133	+1.588	<.001	.005	3	8
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.104	-1.104	.001	.008	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,501 associations by consensus.

Positive regulation of DNA metabolic process by ARHGAP4 expression — BONE

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