ARHGAP39

Across TCGA patient cohorts, ARHGAP39 protein abundance is significantly associated with the RNA expression of many other genes, with 6,597 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGAP39-associated genes across cancer lineages are SYNGR1, ARSB, and ICA1L. Each is linked with ARHGAP39 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARHGAP39-to-partner and partner-to-ARHGAP39 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP39 versus SYNGR1 in GBM, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP39→partner) and Y-score (partner→ARHGAP39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SYNGR1 →	+0.828	+0.290	<.001	<.001	3	3
UCEC	ARSB →	-0.605	-0.477	<.001	<.001	3	3
HNSC	ICA1L →	+1.088	+1.006	.002	.005	3	3
LSCC	ANKRD46 →	+0.552	+0.402	.003	.004	3	3
LSCC	NFATC2 →	-0.607	-0.429	<.001	<.001	3	3
LSCC	UQCRB →	+0.378	+0.417	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,597 associations by consensus.

ARHGAP39 vs SYNGR1 — GBM

Explore this scatter interactively →