ARHGAP39

Across TCGA cell cohorts, ARHGAP39 mutation is significantly associated with the RNA expression of many other genes, with 1,114 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARHGAP39-associated genes across cancer lineages are NQO2, GRXCR2, and TRIM51. Each is linked with ARHGAP39 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP39-to-partner and partner-to-ARHGAP39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NQO2 grouped by ARHGAP39-low versus ARHGAP39-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP39→partner) and Y-score (partner→ARHGAP39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NQO2 →	+1.468	+3.199	.002	.007	3	2
BLOOD_Leukemia	GRXCR2 →	+0.048	+3.078	<.001	<.001	3	2
STOMACH	TRIM51 →	+0.022	+4.129	<.001	.007	3	2
BREAST	PRR32 →	+0.043	+3.415	<.001	.004	3	2
LARGE_INTESTINE	AKAP8L →	+0.460	+3.169	.002	.009	3	2
LARGE_INTESTINE	RPA2 →	+0.534	+2.714	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,114 associations by consensus.

NQO2 by ARHGAP39 expression — BLOOD_Leukemia

Explore this box plot interactively →