ARHGAP36

Across TCGA patient cohorts, ARHGAP36 protein abundance is significantly associated with the RNA expression of many other genes, with 249 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ARHGAP36-associated genes across cancer lineages are MTHFD1, PROCR, and SRPX. Each is linked with ARHGAP36 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP36-to-partner and partner-to-ARHGAP36 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP36 versus MTHFD1 in BRCA, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP36→partner) and Y-score (partner→ARHGAP36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MTHFD1 →	+0.594	+0.613	.001	.007	3	1
BRCA	PROCR →	-1.130	-0.774	.007	.001	3	1
BRCA	SRPX →	-1.544	-0.521	.002	.005	3	1
BRCA	TIMP1 →	-1.501	-0.785	.001	.001	3	1
BRCA	WFDC1 →	-0.925	-0.614	.001	.001	3	1
BRCA	ASF1B →	+1.416	+0.943	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 249 associations by consensus.

ARHGAP36 vs MTHFD1 — BRCA

Explore this scatter interactively →