ARHGAP36

Across TCGA cell cohorts, ARHGAP36 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARHGAP36-associated genes across cancer lineages are COL6A5, PFN3, and LCN6. Each is linked with ARHGAP36 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP36-to-partner and partner-to-ARHGAP36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COL6A5 grouped by ARHGAP36-low versus ARHGAP36-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP36→partner) and Y-score (partner→ARHGAP36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	COL6A5 →	+0.061	+3.760	<.001	.008	3	1
LUNG_NSCLC_LUAD	PFN3 →	+0.923	+3.760	<.001	.008	3	1
LUNG_NSCLC_LUAD	LCN6 →	+0.077	+4.215	<.001	.002	3	1
SKIN	OR2T1 →	+0.006	+4.022	<.001	.006	3	1
SKIN	CCER1 →	+0.031	+4.022	<.001	.006	3	1
LARGE_INTESTINE	EPX →	+0.050	+3.520	.004	.005	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

COL6A5 by ARHGAP36 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →