ARHGAP35

Across TCGA patient cohorts, ARHGAP35 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,821 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGAP35-associated proteins across cancer lineages are XRCC1, THEMIS2, and TRIM28. Each is linked with ARHGAP35 in more than 5 cancer types. Because this analysis shows association rather than direction, both ARHGAP35-to-partner and partner-to-ARHGAP35 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP35 versus XRCC1 in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP35→partner) and Y-score (partner→ARHGAP35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XRCC1 →	+0.359	+0.627	<.001	<.001	3	6
GBM	THEMIS2 →	-0.446	-0.471	<.001	<.001	3	6
GBM	TRIM28 →	+0.301	+0.334	<.001	<.001	3	6
HNSC	UNC13D →	-0.372	-0.546	<.001	.001	3	6
GBM	WDR5 →	+0.239	+0.313	.002	.007	3	6
GBM	SAE1 →	+0.307	+0.405	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,821 associations by consensus.

ARHGAP35 vs XRCC1 — LSCC

Explore this scatter interactively →