ARHGAP35

Across TCGA patient cohorts, ARHGAP35 protein abundance is significantly associated with the RNA expression of many other genes, with 16,325 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGAP35-associated genes across cancer lineages are ZNF419, CADM4, and ERCC1. Each is linked with ARHGAP35 in more than 5 cancer types. Because this analysis shows association rather than direction, both ARHGAP35-to-partner and partner-to-ARHGAP35 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP35 versus ZNF419 in GBM, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP35→partner) and Y-score (partner→ARHGAP35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZNF419 →	+0.456	+0.195	<.001	<.001	3	6
HNSC	CADM4 →	+0.870	+0.209	<.001	<.001	3	6
OV	ERCC1 →	+0.709	+0.398	<.001	<.001	3	6
HNSC	ZNF576 →	+0.480	+0.241	.003	<.001	3	6
BRCA	ZNF776 →	+0.648	+0.415	<.001	<.001	3	6
BRCA	ZNF180 →	+0.600	+0.508	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,325 associations by consensus.

ARHGAP35 vs ZNF419 — GBM

Explore this scatter interactively →