ARHGAP32

Across TCGA patient cohorts, ARHGAP32 mutation is significantly associated with the RNA expression of many other genes, with 6,110 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP32-associated genes across cancer lineages are OIP5, GAPDH, and TPI1. Each is linked with ARHGAP32 in more than 4 cancer types. Because this analysis shows association rather than direction, both ARHGAP32-to-partner and partner-to-ARHGAP32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OIP5 grouped by ARHGAP32-low versus ARHGAP32-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP32→partner) and Y-score (partner→ARHGAP32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	OIP5 →	+0.690	+3.357	.007	.005	3	5
COAD	GAPDH →	+0.543	+2.920	<.001	<.001	3	5
COAD	TPI1 →	+0.504	+2.827	<.001	.001	3	5
UCEC	NARF →	+0.276	+1.222	<.001	<.001	3	5
LUAD	CDCA5 →	+0.901	+3.339	.003	.005	3	5
COAD	WDR76 →	+0.702	+3.933	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,110 associations by consensus.

OIP5 by ARHGAP32 expression — LUAD

Explore this box plot interactively →