ARHGAP31

Across TCGA cell cohorts, ARHGAP31 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,611 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARHGAP31-associated GO terms across cancer lineages are Maintenance of protein location in cell, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Actin filament depolymerization. Each is linked with ARHGAP31 in more than 12 cancer types. Because this analysis shows association rather than direction, both ARHGAP31-to-partner and partner-to-ARHGAP31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of protein location in cell grouped by ARHGAP31-low versus ARHGAP31-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP31→partner) and Y-score (partner→ARHGAP31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Maintenance of protein location in cell →	+0.129	+1.688	<.001	<.001	3	13
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.089	+0.601	<.001	.001	3	13
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.213	+1.417	<.001	.002	3	12
LUNG_NSCLC_LUSC	PML body organization →	+0.216	+1.389	<.001	<.001	3	12
CNS	Negative regulation of Rho protein signal transduction →	+0.161	+1.490	<.001	<.001	3	12
LIVER	Skeletal muscle fiber development →	+0.186	+1.634	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,611 associations by consensus.

Maintenance of protein location in cell by ARHGAP31 expression — LIVER

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