ARHGAP31-AS1

Across TCGA pan-cancer cohorts, ARHGAP31-AS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of ARHGAP31-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ARHGAP31-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ARHGAP31-AS1 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, HNSC, and LUAD are the cancer types where ARHGAP31-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ARHGAP31-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	IV	−1.437	<.001	11	view →
HNSC	Male	All	+0.510	.004	8	view →
LUAD	All	All	+0.468	<.001	5	view →
KIRC	All	All	+0.287	<.001	5	view →
CHOL	Male	All	+1.575	<.001	2	view →
KIRP	All	All	+0.477	.011	2	view →
LUSC	All	All	+0.422	.007	2	view →
BRCA	All	III,IV	−0.351	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

ARHGAP31-AS1–THCA

Open the THCA breakdown →